FAPI: Fast and Accurate P-value Imputation for genetic association

Links of MX Li's tools:


FAPI is a powerful multi-thread Java-based application developed to infer p-values of untyped Single-nucleotide polymorphisms (SNPs) through p-values of SNPs in LD with the untyped one. With similar imputation accuracy to other genotype imputation tools (including IMPUTE and MACH), FAPI is superfast, without requiring phases of reference genotypes and any sample raw genotypes.

Currently FAPI has three main function:

Impute p-value




Assese Quality

FAPI V0.1 has been released! Donwload it! and See Online Manual

Advantages of FAPI :
  • Superfast
  • No need genotypes of original samples
  • Accurate
Comments and suggestions are welcome, please e-mail limx54@163.com
    Kwan JS^, Li MX^*, Deng JE, Sham PC*.FAPI: Fast and Accurate P-value Imputation for genome-wide association study. Eur J Hum Genet. 2016 May;24(5):761-6. doi: 10.1038/ejhg.2015.190. PubMed

Miao-xin Li,Professor on Precision Medical Genetics & Bioinformatics, Zhongshan School of Medicine, Sun Yat-sen University, All rights reserved.