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|
 18/12/2011 |
| Fixed bugs in the function of exporting integrated genotypes |
| 26/02/2011 |
| Fixed bugs in the function of integrating HapMap phased genotypes on X chromosome. Treat malesĄŻ genotypes on X chromosomes as homozygous.
|
| 28/10/2010 |
1. Recognize HapMap data with various reference genome coordinates: Build 35, 36 and 37.
2. Export data for imputation with various reference genome coordinates: Build 35, 36 and 37.
|
| 18/06/2010 |
| Support the Plink binary PED format(http://pngu.mgh.harvard.edu/~purcell/plink/data.shtml#bed). Input and output the *.bed, *.fam, and *.bim files.
|
| 14/04/2010 |
| Modify the confused pedigree input and add a hint to set maximal memory.
|
| 20/11/2009 |
| Optimize the usage of computational memory to handle hundreds of thousands of large SNP chips more efficiently.
|
| 19/10/2009 |
1. Convert non-AB chip genotypes into the AB format genotypes.
2. Enable fast and direct downloading of HapMap phased and unphased genotypes.
|
| 06/09/2009 |
| 1. Fasten the downloading of annotation data by a new http function |
| 05/07/2009 |
| 1. Allow genotypes of SNP with no strand information but non-complementary allele names to be integrated |
| 20/06/2009 |
1. Add more SNPs in the dbSNP annotation dataset
2. Export unphased reference panel genotypes for IMPUTE2
|
| 11/05/2009 |
1. Update the Affymetrix annotation to be na28
2. Add a function to check the latest version of IGG
3. Add a function to summarize the SNPs unexpected allele names
|
| 23/03/2009 |
1. A new input format for general genotype datasets with known strand formation has been added, which flexibly covers many popular formats supported by genetic tools including the linkage package and Plink.
2. A new export format for BIMBAM (http://quartus.uchicago.edu/~yguan/bimbam/index.html) has been added. |
| 07/02/2009 |
| Several minor bugs of IGG3 are fixed for Mac OS. |
| 01/01/2009 |
IGG3 beta is released. It has the following features.
1. Very fast integration of whole-genome genotypes for poplular Affymetrix and Illumina DNA chips;
2.
Ability to integrate whole-genome genotypes of tens of thousand subjects;
3.
Integration of PHASED and unphased HapMap genotypes of Phase I+II+III;
4.
Specical functional module to ease genotype impuation. |
| 07/09/2008 |
| A big update of IGG. It has a complete set of Illumina and Affymetrix gene chips; faster integration; easier useage. |
| 30/06/2008 |
| Add Illumina Human Linkage-12 |
| 24/04/2008 |
| Add Illumina HumanHap550-Duo and Illumina Human CNV 370-Duo |
| 18/02/2008 |
| Add a summary how many markers there are per centiMorgan and per million bases |
| 08/1/2007 |
| Add functions for advanced users to merge large datasets |
| 07/12/2007 |
| Add a function for users to remove genotypes violating Mendelian Law |
| 05/16/2007 |
| Add functions for advanced users to replace annotation files |
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